Navigating GLP‑1 Medications, Constipation, and Your Gut Microbiome
It’s no secret: GLP‑1 receptor agonists—like semaglutide, liraglutide, dulaglutide—have transformed metabolic and weight‑management treatments. But as our clinical practice continues to reveal, many people experience a troubling shift toward constipation or slowed motility after starting these medications. Could the gut microbiome be playing a hidden role in both the benefits of GLP-1s as well as constipation?